Preheat oven to 375°F and line a small loaf pan or baking sheet with parchment paper.
In a large mixing bowl, combine the ground beef, quick oats, egg, diced onion, minced garlic, dried oregano, sea salt, and black pepper.
Gently mix the ingredients by hand until just combined, being careful not to overwork the meat to maintain a tender texture.
Shape the mixture into a uniform loaf and place it on the prepared baking surface.
In a small bowl, whisk together the tomato paste, balsamic vinegar, and honey to create the savory glaze.
Spread the glaze evenly over the top and sides of the meatloaf.
Bake for 35 to 40 minutes, or until the internal temperature reaches 160°F and the glaze is bubbly and caramelized.
Allow the meatloaf to rest for 5 minutes before slicing to ensure the juices redistribute for a moist result.