Bring a large pot of salted water to a boil and cook the whole wheat penne according to package instructions until al dente.
While the pasta cooks, season the chicken breast evenly with the sea salt, black pepper, and dried oregano.
Heat a large skillet over medium-high heat and sear the chicken for 5-6 minutes per side until the internal temperature reaches 165 degrees Fahrenheit.
Remove the chicken from the skillet, let it rest for 2 minutes, and then slice it into thin strips.
In the same skillet, reduce the heat to medium and add the ghee and minced garlic, sautéing for 1 minute until fragrant and golden.
Add the cooked pasta, sliced chicken, and fresh spinach to the skillet, tossing constantly until the spinach is just wilted.
Garnish with freshly chopped parsley and serve immediately while hot.