Preheat your oven to 425°F.
Pat the salmon fillet dry with paper towels to ensure a crispy skin. Season both sides lightly with salt and pepper.
In a small bowl, combine the maple syrup, Dijon mustard, and red pepper flakes to create the spicy glaze.
Heat a non-stick, oven-safe skillet over medium-high heat. Once hot, place the salmon fillet skin side down and cook for about 3-4 minutes until the skin is crispy.
While the salmon is searing, toss the Brussels sprouts with olive oil, salt, and pepper on a baking sheet.
Place the Brussels sprouts into the preheated oven and roast for about 12-15 minutes, stirring halfway through for even browning.
After the skin has crisped, flip the salmon and brush the top generously with the spicy maple glaze. Transfer the skillet to the oven and bake for an additional 5-7 minutes, or until the salmon is just cooked through.
Once done, remove both the salmon and Brussels sprouts from the oven. Plate them together and drizzle any remaining glaze over the salmon.
Serve immediately and enjoy the harmonious blend of rich, savory salmon with a kick of spice and the freshness of roasted Brussels sprouts.