Preheat your oven to 425°F and line a baking sheet with parchment paper. Lightly coat the sheet with cooking spray.
Pound the chicken breast to even thickness if necessary. Pat dry with paper towels.
In a shallow dish, whisk the egg white until slightly frothy. In another small bowl, place the panko breadcrumbs.
Dip the chicken breast first into the egg white, then dredge evenly in the panko breadcrumbs to create a light coating.
Place the breaded chicken on the prepared baking sheet, and spray lightly on top to help enhance crispiness.
Bake in the preheated oven for 18-20 minutes until the chicken is thoroughly cooked and the coating is golden and crispy.
While the chicken bakes, prepare the zesty sticky orange sauce. In a small saucepan, combine the fresh orange juice, honey, minced garlic, grated ginger, and cornstarch.
Heat the mixture over medium heat, stirring constantly until the sauce starts to thicken into a sticky glaze, about 3-4 minutes.
Once the chicken is done, remove it from the oven. Drizzle the warm, zesty sauce generously over the crispy chicken.
Serve immediately and enjoy your crispy baked orange chicken with a burst of citrusy, zesty flavor.