Preheat your oven to 425°F.
Pat the salmon dry with paper towels and season generously with blackened seasoning, salt, and pepper on both sides.
Place the salmon fillet on a baking sheet lined with parchment paper. Roast in the oven for 10-12 minutes, until the salmon is just opaque in the center.
While the salmon bakes, trim the tough ends from the asparagus. Toss the asparagus with olive oil, salt, and pepper, and lay them out on a separate baking sheet.
Roast the asparagus in the oven for 8-10 minutes alongside the salmon, until tender but still crisp.
Prepare the creamy avocado sauce by mashing the avocado in a bowl. Stir in the Greek yogurt and fresh lime juice. Adjust seasoning with salt and pepper to taste.
Once the salmon and asparagus are finished, plate the salmon, drizzle the avocado sauce over the top or serve on the side, and arrange the roasted asparagus.
Serve immediately and enjoy the vibrant mix of flavors.