Preheat your oven to 425°F and line a baking sheet with parchment paper or a silicone mat.
In a shallow bowl, combine the low-fat buttermilk with garlic powder, paprika, salt, and pepper.
Place the chicken breast between two sheets of plastic wrap and gently pound to an even thickness for uniform cooking.
Submerge the chicken breast in the buttermilk mixture and let it marinate for at least 30 minutes in the fridge.
In another shallow dish, spread the whole wheat breadcrumbs.
Remove the chicken from the buttermilk marinade, letting any excess drip off, then lightly dredge it in the breadcrumbs, ensuring an even, thin coating.
Place the coated chicken breast on the prepared baking sheet. Lightly spray the top with olive oil spray to help crisping.
Bake for 20-25 minutes or until the chicken reaches an internal temperature of 165°F and the coating is golden and crispy.
Remove from the oven, let it rest for a few minutes, then serve and enjoy.