Begin by preheating your grill or grill pan over medium-high heat.
In a small bowl, mix the olive oil, lime juice, chili powder, garlic powder, ground cumin, salt, and pepper to create a spicy marinade.
Coat the chicken breast evenly with the marinade. Let it sit for 10-15 minutes to absorb the flavors.
Place the marinated chicken on the grill and cook for about 5-6 minutes per side or until the internal temperature reaches 165°F.
While the chicken grills, wash and pat dry the romaine lettuce leaves and slice the red bell pepper into thin strips.
Slice the avocado into cubes or thin slices.
Once cooked, let the chicken rest for a couple of minutes before slicing it into bite-sized strips.
Assemble the lettuce wraps by placing chicken pieces on each leaf, then topping with red bell pepper and avocado.
Drizzle any remaining lime marinade over the wraps for added flavor.
Serve immediately and enjoy your fresh, spicy, and creamy wraps.