Preheat your oven to 400°F and line a baking sheet with parchment paper.
In a shallow dish, pour the buttermilk. Season the chicken breast with salt, pepper, paprika, and garlic powder, then place it into the buttermilk, ensuring it is well-coated. Allow the chicken to marinate for at least 20 minutes, or up to 1 hour in the refrigerator for deeper flavor.
In a separate plate, spread out the whole wheat breadcrumbs.
Remove the chicken from the buttermilk, letting the excess drip off, and dredge it in the breadcrumbs, pressing lightly to ensure an even coating.
Place the breadcrumb-coated chicken on the prepared baking sheet and lightly spray the top with olive oil cooking spray to help create a crispy exterior.
Bake in the preheated oven for 20-25 minutes, or until the chicken is cooked through and the coating is golden and crispy. An internal temperature of 165°F is recommended.
Remove from the oven and let rest for a few minutes before serving. Enjoy your crispy, healthier version of a comfort food classic!