Preheat your oven to 400°F (200°C) and line a baking sheet with parchment paper.
Trim the woody ends off the asparagus and toss the spears on the baking sheet with half of the olive oil and a pinch of salt and pepper.
Roast the asparagus for 12-15 minutes until tender and slightly crisp at the tips.
While the asparagus roasts, season the chicken breast evenly with the dried oregano and the remaining salt and pepper.
Heat the remaining olive oil in a medium skillet over medium-high heat.
Place the chicken in the skillet and sear for 6-7 minutes per side, or until the internal temperature reaches 165°F.
Add the minced garlic to the pan during the last minute of cooking, stirring constantly to avoid burning.
Pour the lemon juice and lemon zest into the skillet, swirling it around to coat the chicken in the bright pan sauce.
Plate the chicken alongside the roasted asparagus and drizzle any remaining pan juices over the top.