In a medium bowl, combine the ground turkey, egg, almond flour, parmesan cheese, and half of the garlic powder, onion powder, salt, and pepper.
Gently mix the ingredients until just combined, then roll into small, uniform meatballs.
Heat the olive oil in a non-stick skillet over medium heat and brown the meatballs on all sides for about 5-6 minutes.
Pour the tomato puree into the skillet and stir in the remaining garlic powder, onion powder, salt, pepper, dried oregano, and red pepper flakes.
Reduce the heat to low, cover, and simmer for 10 minutes until the sauce thickens into a glaze and the meatballs are cooked through.
While the sauce simmers, lightly steam or sauté the zucchini noodles for 2 minutes until tender-crisp.
Serve the glazed meatballs and zesty sauce over the zucchini noodles and enjoy immediately.