Preheat your oven to 400°F (200°C) and line a large sheet pan with parchment paper.
Dice the sweet potato into 1/2-inch cubes and trim the woody ends off the asparagus spears.
In a small mixing bowl, whisk together the olive oil, lemon juice, lemon zest, dried oregano, garlic powder, sea salt, and black pepper.
Place the chicken breast, cubed sweet potatoes, and asparagus on the prepared baking sheet.
Brush the herb and lemon mixture generously over the chicken breast and toss the vegetables to ensure they are evenly coated.
Roast in the center of the oven for 20 to 25 minutes, or until the chicken reaches an internal temperature of 165°F.
Add the cherry tomatoes to the pan during the final 5 minutes of roasting until they are blistered and soft.
Remove from the oven and let the chicken rest for 5 minutes before slicing to keep it juicy.