Boil a pot of salted water and cook the whole wheat penne according to package directions until al dente, reserving two tablespoons of pasta water before draining.
While the pasta cooks, heat the olive oil in a large skillet over medium-high heat and sear the chicken pieces with sea salt and black pepper until golden and fully cooked.
Remove the chicken from the skillet and set aside, then add the sliced cremini mushrooms to the same pan and sauté until they release their moisture and turn a deep golden brown.
Stir in the minced garlic and cook for one minute until fragrant, then pour in the chicken broth to deglaze the pan, scraping up any browned bits from the bottom.
Lower the heat to a simmer and whisk the Greek yogurt and truffle oil together in a small bowl before stirring the mixture into the skillet to create a smooth sauce.
Add the cooked pasta, seared chicken, and the reserved pasta water to the skillet, tossing gently to ensure every noodle is coated in the creamy truffle sauce.
Garnish the dish with grated parmesan cheese and fresh chopped parsley before serving immediately while warm.