Heat a large skillet over medium-high heat until hot.
Add the ground beef to the skillet, breaking it into small crumbles with a spatula.
Season the beef with sea salt, black pepper, and garlic powder.
Cook the beef undisturbed for 3-4 minutes to develop a crust, then stir and continue cooking until browned and crispy.
While the beef cooks, whisk together the Greek yogurt, yellow mustard, pickle juice, and smoked paprika in a small bowl.
Place the shredded romaine lettuce into a large serving bowl as the base.
Top the lettuce with the cooked crispy beef, diced pickles, red onion, and halved cherry tomatoes.
Add the avocado slices to the bowl and drizzle the prepared yogurt sauce over all the ingredients.
Finish the bowl with a sprinkle of sesame seeds and serve immediately.