Preheat your oven to 400°F and line a large baking sheet with parchment paper for easy cleanup.
In a medium bowl, toss the broccoli florets and sliced red bell peppers with half of the olive oil, sea salt, and dried oregano.
Spread the vegetables in a single layer on the prepared baking sheet and roast for 15-18 minutes until the edges are slightly charred and tender.
While the vegetables roast, pat the salmon fillet completely dry with a paper towel and season both sides with garlic powder and black pepper.
Heat the remaining olive oil in a high-quality non-stick skillet over medium-high heat until the oil is shimmering.
Carefully place the salmon skin-side down in the pan and sear for 4-5 minutes without moving it to ensure the skin becomes crispy and golden.
Flip the fillet gently and cook for an additional 2-3 minutes until the salmon is opaque throughout and flakes easily with a fork.
Plate the crispy salmon alongside the zesty roasted vegetables and finish the dish with a bright drizzle of fresh lemon juice.