Bring a pot of salted water to a boil and cook the whole wheat pasta according to package directions until al dente.
While pasta cooks, heat olive oil in a large skillet over medium-high heat and sauté the diced chicken breast until golden and cooked through.
Add the sliced zucchini, halved cherry tomatoes, and minced garlic to the skillet, cooking for 3-4 minutes until the vegetables are tender and tomatoes begin to burst.
In a small bowl, whisk together the Greek yogurt, lemon juice, sea salt, black pepper, and red pepper flakes until smooth.
Drain the pasta, reserving two tablespoons of pasta water, then toss the pasta and reserved water into the skillet with the chicken and vegetables.
Remove the skillet from heat and stir in the yogurt mixture until the pasta is coated in a velvety, creamy sauce.