Preheat your oven to 400°F (200°C) and line a small baking sheet with parchment paper.
Trim the woody ends off the asparagus and toss them on the baking sheet with the olive oil, half of the sea salt, and half of the black pepper.
Pat the chicken breast dry with a paper towel and season both sides with the remaining salt, pepper, and the dried oregano.
Heat a cast iron skillet over medium-high heat and add the ghee, swirling the pan to coat the surface evenly.
Place the chicken in the skillet and sear for 5-6 minutes per side until a deep golden-brown crust forms and the internal temperature reaches 165°F.
While the chicken is searing, slide the asparagus into the oven and roast for 10-12 minutes until tender yet crisp.
In a small bowl, whisk together the lemon juice, lemon zest, honey, and minced garlic to create the glaze.
Reduce the skillet heat to low, pour the lemon mixture over the chicken, and spoon the bubbling sauce over the meat for 1 minute until slightly thickened.
Plate the chicken alongside the roasted asparagus and drizzle any remaining pan glaze over the top before serving.