Preheat your oven to 400°F (200°C) and line a large rimmed baking sheet with parchment paper.
Trim the woody ends off the Brussels sprouts and slice them in half lengthwise.
Cut the chicken breast into uniform 1-inch cubes to ensure even cooking.
In a large mixing bowl, combine the chicken and Brussels sprouts with olive oil, sea salt, black pepper, and garlic powder.
Toss everything together until the ingredients are thoroughly and evenly coated with the oil and spices.
Spread the mixture onto the prepared baking sheet in a single layer, making sure the Brussels sprouts are cut-side down for maximum browning.
Roast for 20 to 25 minutes, tossing the ingredients halfway through, until the chicken is cooked through and the sprouts are charred and tender.
Remove from the oven and immediately drizzle with the balsamic glaze and honey, tossing gently to coat while still hot.