Bring a pot of salted water to a boil and cook the whole wheat penne according to package directions until al dente. Reserve 1/4 cup of pasta water before draining.
While the pasta cooks, heat the olive oil in a large skillet over medium-high heat.
Add the diced chicken breast to the skillet and cook until golden brown and cooked through, approximately 5-7 minutes.
Add the sliced mushrooms and minced shallot to the skillet, sautéing until the mushrooms are tender and the shallots are translucent.
Stir in the minced garlic and cook for 1 minute until fragrant.
In a small bowl, whisk together the plain Greek yogurt, truffle oil, sea salt, and black pepper.
Reduce the skillet heat to low. Add the cooked pasta and the yogurt mixture to the pan.
Gradually add the reserved pasta water one tablespoon at a time, tossing everything together until a creamy sauce coats the pasta.
Remove from heat and garnish with fresh chopped parsley before serving immediately.