Preheat your oven to 400°F (200°C) and line a large baking sheet with parchment paper.
In a medium mixing bowl, combine the Greek yogurt and self-rising flour, stirring until a shaggy dough forms.
Transfer the dough to a lightly floured surface and knead by hand for 1-2 minutes until the dough is smooth and no longer sticky.
Roll the dough out into a 10-inch circle directly onto the prepared parchment paper.
Slice 1.5 ounces of the mozzarella cheese into thin strips and arrange them in a circle about 1 inch from the edge of the dough.
Fold the outer edge of the dough over the cheese strips and press down firmly to create a sealed, stuffed crust border.
Spread the tomato puree evenly over the center of the pizza dough.
Sprinkle the oregano, garlic powder, sea salt, and black pepper over the sauce.
Shred the remaining 0.5 ounce of mozzarella and sprinkle it over the sauce, then layer the turkey pepperoni slices on top.
Bake for 12-15 minutes, or until the crust is golden brown and the cheese in the center is bubbly and melted.