Preheat your oven to 400°F (200°C) and line a large rimmed baking sheet with parchment paper for easy cleanup.
Trim the tough, woody ends off the asparagus spears and spread them out on one side of the prepared baking sheet.
Place the salmon fillet on the other side of the baking sheet, skin-side down.
In a small glass bowl, whisk together the extra virgin olive oil, fresh lemon juice, lemon zest, minced garlic, and dried oregano.
Drizzle the lemon-herb mixture evenly over both the salmon and the asparagus, using a brush or spoon to ensure the salmon is well coated.
Season the entire sheet pan with sea salt and freshly cracked black pepper.
Slide the baking sheet into the oven and bake for 12 to 15 minutes, depending on the thickness of the fillet, until the salmon is opaque and flakes easily.
Remove from the oven and garnish with a sprinkle of freshly chopped parsley before serving immediately.