Heat a non-stick skillet over medium-high heat.
Add the ground beef, sea salt, black pepper, and garlic powder to the skillet.
Cook the beef, breaking it apart with a spatula, until it is browned and cooked through.
While the beef cooks, chop the romaine lettuce, halve the cherry tomatoes, and finely dice the red onion and pickles.
In a small bowl, whisk together the Greek yogurt, unsweetened ketchup, yellow mustard, and pickle relish to create the special sauce.
Place the shredded romaine lettuce in a large bowl as the base.
Top the lettuce with the cooked ground beef, cherry tomatoes, red onion, and pickles.
Sprinkle the sharp cheddar cheese over the warm beef so it begins to melt.
Drizzle the special sauce over the entire bowl and serve immediately.