Preheat your oven to 400°F (200°C) and line a large rimmed baking sheet with parchment paper for easy cleanup.
Pat the chicken breast completely dry with a paper towel to ensure the herbs stick and the meat browns beautifully.
In a small glass bowl, whisk together the extra virgin olive oil, dried oregano, garlic powder, sea salt, and black pepper.
Place the chicken breast on one side of the baking sheet and brush it thoroughly with half of the herb and oil mixture.
Roast the chicken in the center of the oven for 10 minutes to give it a head start on cooking.
While the chicken is roasting, trim the woody ends off the asparagus spears and toss them in the remaining herb oil.
Carefully remove the baking sheet from the oven, arrange the asparagus in a single layer next to the chicken, and return to the oven for 12-15 minutes.
Once the chicken reaches an internal temperature of 165°F and the asparagus is vibrant, remove from the oven and immediately finish with fresh lemon juice and zest.