Preheat your oven to 400°F (200°C). Scrub the Russet potato clean and pierce it several times with a fork.
Bake the potato directly on the oven rack for 45-50 minutes until the skin is crisp and the inside is tender.
While the potato bakes, heat a non-stick skillet over medium-high heat. Add the ground turkey, breaking it apart with a spatula.
Season the turkey with chili powder, cumin, garlic powder, onion powder, sea salt, and black pepper. Cook until browned and no longer pink.
Stir in the tomato sauce and diced red onion, simmering for 2-3 minutes until the flavors meld. Remove from heat.
Once the potato is done, let it cool slightly. Slice it in half lengthwise and scoop out most of the flesh, leaving about a 1/4-inch layer against the skin.
Fill each potato skin half with the turkey chili mixture and top evenly with shredded sharp cheddar cheese.
Place the loaded skins on a baking sheet and broil for 2-3 minutes until the cheese is bubbly and golden brown.
Garnish with freshly chopped cilantro before serving.