Preheat your oven to 400°F (200°C) and line a large rimmed baking sheet with parchment paper for easy cleanup.
Trim the tough, woody ends off the asparagus spears and arrange them in a single layer on one side of the prepared baking sheet.
Place the salmon fillet on the other side of the baking sheet, skin-side down.
In a small bowl, whisk together the extra virgin olive oil, fresh lemon juice, lemon zest, minced garlic, dried oregano, sea salt, and black pepper.
Drizzle the lemon-herb mixture evenly over both the salmon and the asparagus, using a brush or your hands to ensure the vegetables are well coated.
Slide the baking sheet into the oven and roast for 12 to 15 minutes, or until the salmon is opaque and flakes easily with a fork.
Remove from the oven and serve the salmon immediately alongside the tender-crisp asparagus with an optional extra squeeze of lemon.