Preheat your oven to 400°F (200°C) and line a large rimmed baking sheet with parchment paper for easy cleanup.
Wash the asparagus and trim away the tough, woody ends, then spread the spears across one half of the prepared baking sheet.
Place the salmon fillet on the other half of the baking sheet, ensuring it is patted dry with a paper towel.
In a small glass bowl, whisk together the olive oil, fresh lemon juice, lemon zest, minced garlic, and dried oregano until well combined.
Drizzle the lemon-herb mixture evenly over both the salmon and the asparagus, then season everything with the sea salt and black pepper.
Bake in the center of the oven for 12-15 minutes, or until the salmon is opaque and flakes easily with a fork and the asparagus is tender.
Remove from the oven and garnish with fresh chopped parsley before serving immediately.