Bring a large pot of salted water to a boil and cook the brown rice penne according to package directions until al dente.
While the pasta cooks, crumble the organic tempeh into small, bite-sized pieces.
Heat the extra virgin olive oil in a large skillet over medium-high heat and add the crumbled tempeh and minced garlic, sautéing until the tempeh is golden brown.
Add the sliced zucchini and diced red bell pepper to the skillet, cooking for 3-4 minutes until the vegetables are tender-crisp.
Stir in the shelled edamame and baby spinach, cooking just until the spinach is wilted.
Drain the pasta, reserving 2 tablespoons of the cooking water.
Add the cooked pasta, reserved water, nutritional yeast, fresh lemon juice, sea salt, black pepper, and red pepper flakes to the skillet.
Toss everything together until the pasta is evenly coated in the savory sauce and serve immediately.