Preheat your oven to 400°F (200°C) and line a large rimmed baking sheet with parchment paper for easy cleanup.
Wash the asparagus and snap off the tough, woody bottom ends, then place the spears on one side of the prepared baking sheet.
Pat the salmon fillet dry with a paper towel and place it on the other side of the baking sheet.
In a small glass bowl, whisk together the olive oil, lemon juice, lemon zest, minced garlic, and dried oregano until well combined.
Drizzle the lemon-herb mixture evenly over both the salmon fillet and the asparagus spears.
Season everything with the sea salt and freshly cracked black pepper.
Bake for 12 to 15 minutes, depending on the thickness of the fillet, until the salmon is opaque and flakes easily with a fork and the asparagus is tender.
Serve immediately, garnishing with extra fresh herbs or a lemon wedge if desired.