Preheat your oven to 400°F (200°C) and line two large sheet pans with parchment paper for easy cleanup.
Cut the chicken breasts into 1-inch bite-sized pieces and peel and cube the sweet potatoes into 1/2-inch pieces.
Trim the Brussels sprouts and cut them in half, then break the broccoli into small, bite-sized florets.
Distribute the chicken, sweet potatoes, broccoli, and Brussels sprouts evenly across the two prepared sheet pans.
Drizzle the olive oil over everything, then sprinkle with sea salt, black pepper, garlic powder, and smoked paprika.
Use your hands or a spatula to toss everything until thoroughly coated, then spread into a single layer.
Roast for 20 to 25 minutes, or until the chicken is cooked through and the vegetables are tender and slightly caramelized.
Divide the mixture evenly into five meal-prep containers for a week of healthy, high-protein lunches.