Preheat your oven to 425°F and line a baking sheet with parchment paper.
Slice the sweet potato into thin, even wedges and place them on the baking sheet.
Drizzle the sweet potatoes with half of the olive oil and season with half of the salt and pepper.
Roast the sweet potatoes for 20 to 25 minutes, flipping halfway through, until they are crispy and tender.
In a medium bowl, combine the ground chicken with the garlic powder, onion powder, and the remaining salt and pepper.
Form the chicken mixture into two equal-sized patties, ensuring they are even in thickness.
Heat the remaining olive oil in a non-stick skillet over medium-high heat.
Add the chicken patties to the skillet and cook for 5 to 6 minutes per side until the internal temperature reaches 165°F and the exterior is golden brown.
Place each chicken burger inside a large butter lettuce leaf to serve as a wrap.
Top the burgers with the tomato and red onion slices and serve immediately with the hot sweet potato fries on the side.