Preheat your oven to 400°F and line a large baking sheet with parchment paper.
Toss the cubed red potatoes with half of the olive oil and a pinch of the salt, pepper, and garlic powder.
Spread the potatoes on the baking sheet and roast for 15 minutes until they begin to soften.
Add the broccoli, sliced zucchini, and green beans to the baking sheet, tossing with the remaining oil and roasting for another 10-12 minutes until tender.
While the vegetables roast, heat a large skillet over medium-high heat and add the ground chicken and ground beef.
Cook the meats together, breaking them into small crumbles with a spatula, until browned and cooked through.
Drain any excess liquid from the skillet and stir in the onion powder, smoked paprika, and the remaining salt, pepper, and garlic powder.
Transfer the roasted potatoes and vegetables into the skillet, tossing gently to combine all the flavors before serving.