Preheat your oven to 400°F (200°C) and line a baking sheet with parchment paper.
In a medium mixing bowl, combine the Greek yogurt, whole wheat flour, baking powder, and sea salt until a shaggy dough forms.
Transfer the dough to a lightly floured surface and knead for 2-3 minutes until the dough is smooth and no longer sticky.
Roll the dough into a 7-inch circle and place it on the prepared baking sheet.
Pre-bake the crust for 6 minutes to ensure it remains firm and holds the toppings well.
While the crust is pre-baking, brown the ground turkey in a small skillet over medium heat until fully cooked through.
In a small bowl, whisk together the tomato puree, dried oregano, and garlic powder to create the pizza sauce.
Spread the sauce evenly over the pre-baked crust, then layer on the cooked turkey and the shredded mozzarella cheese.
Bake for an additional 8-10 minutes until the cheese is bubbly and the edges of the crust are golden brown.
Remove from the oven, sprinkle with red pepper flakes, and let rest for 2 minutes before slicing.