Press the tofu for 15 minutes to remove excess moisture, then cut into 1-inch cubes.
In a small bowl, whisk together the tamari, toasted sesame oil, nutritional yeast, minced ginger, and minced garlic to create the glaze.
Heat the avocado oil in a large skillet or wok over medium-high heat until shimmering.
Add the tofu cubes to the skillet and sear until golden brown and crisp on all sides, approximately 8-10 minutes.
Add the broccoli florets, sliced red bell pepper, and edamame to the skillet, sautéing for 5 minutes until the vegetables are tender-crisp.
Pour the prepared glaze over the tofu and vegetables, tossing well to ensure everything is evenly coated.
Cook for an additional 2 minutes until the sauce thickens slightly and clings to the ingredients.
Season with sea salt and black pepper, then garnish with sesame seeds before serving hot.