Press the extra firm tofu for 15 minutes to remove excess moisture then cut into 1-inch cubes.
Whisk together the tamari, rice vinegar, grated ginger, and minced garlic in a small bowl to create the stir-fry sauce.
Heat the toasted sesame oil in a large non-stick skillet or wok over medium-high heat.
Add the tofu cubes to the skillet, seasoning with sea salt and black pepper, and sear until golden brown and crispy on all sides.
Toss in the broccoli florets, sliced red bell pepper, and shelled edamame, sautéing for 4 to 5 minutes until the vegetables are tender-crisp.
Pour the prepared sauce over the tofu and vegetables, stirring constantly for 1 to 2 minutes until the glaze coats everything evenly.
Garnish the stir-fry with sesame seeds and red pepper flakes before serving immediately while hot.