In a medium skillet over medium-high heat, brown the ground beef until fully cooked and no longer pink.
Season the beef with the garlic powder, onion powder, sea salt, and black pepper while cooking.
In a small bowl, whisk together the Greek yogurt, yellow mustard, pickle juice, and smoked paprika to create the special sauce.
Wash and chop the romaine lettuce, then place it in a large serving bowl.
Top the lettuce with the cooked ground beef, diced red onion, chopped pickles, halved cherry tomatoes, and shredded cheddar cheese.
Drizzle the creamy special sauce over the bowl and toss gently before serving.