Preheat your oven to 400°F and line a small baking sheet with parchment paper for easy cleanup.
Trim the woody ends off the asparagus and place the spears on the baking sheet.
Mince the garlic clove and toss it with the asparagus, half of the olive oil, and 0.25 tsp of sea salt.
Roast the asparagus in the oven for 12-15 minutes until they are tender and slightly charred at the tips.
While the vegetables roast, pat the salmon fillet completely dry with a paper towel to ensure a good sear.
Season both sides of the salmon with the remaining sea salt, black pepper, and dried oregano.
Heat the remaining olive oil in a stainless steel or cast-iron skillet over medium-high heat until the oil is shimmering.
Place the salmon skin-side down in the hot pan and press down lightly with a spatula for 10 seconds.
Sear the salmon for 4-5 minutes without moving it to allow the skin to become perfectly crispy and golden.
Carefully flip the fillet and cook for another 2-3 minutes until the salmon is opaque and reaches your desired level of doneness.
Plate the salmon alongside the roasted asparagus and finish the entire dish with a bright squeeze of fresh lemon juice.