Preheat your oven to 400°F (200°C) and line a large sheet pan with parchment paper for easy cleanup.
Dice the sweet potato into small 0.5-inch cubes to ensure they roast quickly alongside the salmon.
Chop the broccoli into bite-sized florets and slice the red bell pepper into thin strips.
Place the salmon fillet in the center of the prepared sheet pan and arrange the vegetables in a single layer around it.
Drizzle the olive oil over the salmon and vegetables, then sprinkle evenly with sea salt, black pepper, garlic powder, and dried oregano.
Toss the vegetables gently with a spatula to coat them in the oil and spices, ensuring the salmon is also seasoned.
Roast in the oven for 15 to 18 minutes, or until the salmon is opaque and flakes easily and the vegetables are tender.
Transfer the roasted salmon and vegetables into a bowl and serve immediately while warm.