Preheat your oven to 400°F and line a large baking sheet with parchment paper.
In a large mixing bowl, combine the cauliflower florets and cubed chicken breast with olive oil, garlic powder, onion powder, sea salt, and black pepper.
Toss until everything is evenly coated in the oil and spices.
Spread the mixture in a single layer on the prepared baking sheet, ensuring there is space between pieces for even roasting.
Roast for 20 to 25 minutes, flipping the pieces halfway through, until the chicken is cooked through and the cauliflower has charred, golden edges.
Remove from the oven and immediately transfer the chicken and cauliflower back to the mixing bowl.
Add the buffalo hot sauce and toss gently until every bite is thoroughly glazed.
In a small ramekin, stir together the Greek yogurt and minced chives to create the dipping sauce.
Serve the buffalo bites immediately while warm with the cooling yogurt sauce on the side.