Cut the chicken breast into small, bite-sized cubes and season evenly with garlic powder, sea salt, and black pepper.
Heat a skillet over medium-high heat and sauté the chicken until it is golden brown and cooked through, approximately 6 to 8 minutes.
In a small bowl, whisk together the melted ghee and hot sauce until the mixture is smooth and emulsified.
Lower the heat on the skillet and pour the buffalo sauce over the chicken, tossing well to ensure every piece is thoroughly coated.
Prepare the lettuce wraps by washing and drying the butter lettuce leaves, arranging them on a serving platter.
Finely dice the celery and shred the carrots to use as a cooling topping for the spicy chicken.
In a small ramekin, stir the Greek yogurt with a teaspoon of water if needed to reach a drizzling consistency.
Spoon the buffalo chicken into the lettuce leaves, top with the celery and carrots, and finish with a drizzle of the Greek yogurt sauce.