Preheat your oven to 425°F (220°C).
Press the extra firm tofu between paper towels to remove excess moisture, then crumble it into small, bite-sized pieces in a mixing bowl.
Rinse and drain the cannellini beans, then add them to the bowl with the crumbled tofu.
Add the sliced bell peppers, mushrooms, and red onion to the bowl; toss everything with the olive oil, garlic powder, sea salt, and black pepper until evenly coated.
Place the sprouted grain flatbread on a baking sheet and spread the tomato puree evenly across the surface, leaving a small margin for the crust.
Distribute the tofu, bean, and vegetable mixture over the sauce in a single layer.
Sprinkle the nutritional yeast and dried oregano over the toppings to provide a savory, cheesy flavor profile.
Bake for 12-15 minutes until the vegetables are tender and the edges of the flatbread are golden brown and crispy.
Remove from the oven, let cool for two minutes, and slice into wedges before serving.