Heat a large non-stick skillet over medium-high heat.
Add the ground beef to the skillet, breaking it into small crumbles with a wooden spoon as it cooks.
Once the beef is browned and no longer pink, stir in the chili powder, cumin, garlic powder, sea salt, and black pepper.
Cook for 1-2 additional minutes until the spices are fragrant and well-incorporated into the meat.
In a large serving bowl, arrange the chopped romaine lettuce as a base.
Top the lettuce with the warm seasoned ground beef, halved cherry tomatoes, and diced red onion.
Place the sliced avocado on top and drizzle the entire bowl with fresh lime juice.
Garnish with chopped cilantro and serve immediately.