Heat the toasted sesame oil in a large skillet over medium-high heat until shimmering.
Add the Impossible beef to the pan, breaking it into small crumbles with a spatula, and cook until browned and slightly crispy.
Stir in the minced ginger, minced garlic, and red chili flakes, sautéing for about 1 minute until the aromatics are fragrant.
Whisk together the coconut aminos, fish sauce, maple syrup, and lime juice in a small bowl, then pour the mixture over the beef.
Add the shelled edamame to the skillet and toss everything together, cooking for 2 more minutes to glaze the protein and warm the beans.
Season the mixture with sea salt and black pepper, then remove the skillet from the heat.
Place the shredded Little Gem lettuce into a serving bowl as the base.
Spoon the hot ginger-sesame beef and edamame mixture over the lettuce.
Garnish the bowl with thinly sliced green onions and toasted sesame seeds before serving immediately.