Preheat your oven to 400°F and lightly grease a small oven-safe baking dish.
Toss the cubed butternut squash with olive oil, sea salt, and black pepper on a parchment-lined baking sheet.
Roast the squash for 15 minutes until it is tender and slightly caramelized.
While the squash roasts, brown the ground turkey in a skillet over medium heat, breaking it into small crumbles.
Season the turkey with chili powder and garlic powder, then stir in the rinsed black beans and remove from heat.
Slice the corn tortilla into thin, uniform strips.
Spread a thin layer of enchilada sauce on the bottom of the baking dish to prevent sticking.
Layer half of the tortilla strips, followed by the turkey and bean mixture, and the roasted squash.
Top with the remaining tortilla strips and pour the rest of the enchilada sauce evenly over the surface.
Sprinkle with shredded cheddar cheese and bake for 10-12 minutes until the cheese is melted and the edges are bubbling.
Garnish with a generous dollop of plain Greek yogurt and fresh cilantro before serving.