Preheat your oven to 400°F and line a large rimmed baking sheet with parchment paper for easy cleanup.
Pat the salmon fillet and the peeled, deveined shrimp dry with paper towels to ensure a perfect roast and prevent steaming.
Trim the woody ends off the asparagus spears and place them on one side of the prepared baking sheet.
Place the salmon fillet in the center of the pan and arrange the shrimp on the remaining side.
In a small bowl, whisk together the extra virgin olive oil, lemon juice, minced garlic, sea salt, black pepper, and dried oregano.
Drizzle the lemon-garlic mixture over the salmon, shrimp, and asparagus, using a brush to coat everything evenly.
Bake for 12 to 15 minutes, or until the salmon flakes easily with a fork and the shrimp are pink and opaque.
Remove from the oven and serve immediately, optionally garnishing with a few fresh lemon slices for extra brightness.